"Great product as usual"
Endotelio 1-MNA
Endotelio 1-MNA
Endotelio 1-MNA is a unique supplement that helps block the enzyme NNMT, supporting metabolic, brain, and cellular health by optimizing NAD levels. As a natural byproduct of vitamin B3, 1-MNA also shows anti-inflammatory effects and supports vascular and cardiovascular health, making it a strong candidate for daily use.
- Known to be safe and well-tolerated
- Renowned for its anti-inflammatory and anti-atherosclerotic qualities
- Lowers levels of inflammatory markers
Benefits
Benefits
- Essential for maintaining vascular endothelial function and stimulating synthesis of prostacyclin (PGI2)
- Bolsters the secretory function of the vascular endothelium, thereby safeguarding against dysfunction
- Minimizes the risk of blood clot formation and inflammation via PGI2 synthesis.
- Enhances the stability of sirtuins (Sirt1), which in certain biological models has been associated with extended lifespan
- Considered a groundbreaking molecule with potent anti-inflammatory and anti-atherosclerotic effects
- Leading research institutions suggest 1-MNA may extend human lifespan
- Elevated levels of 1-MNA during exercise and fasting suggest that its consumption, particularly during endurance training, could enhance exercise capacity and improve performance
- Bottle contains 30 capsules
Ingredients
Ingredients
Cellulose (bulking agent), hydroxypropyl methylcellulose (glazing agent), 1-methylnicotinamide chloride (1-MNA), silicon dioxide (anticaking agent).
Purity Promise
Purity Promise
We create clean formulations without unnecessary additives. We select active ingredients based on thorough scientific research that supports our daily needs. We always choose highly absorbable forms of vitamins and minerals. We meticulously select plant extracts to ensure they have proven efficacy and are safe for use. Our products do not contain dyes. Our capsules are transparent and do not contain titanium dioxide (E171), which for years was widely used as a white dye but is no longer considered safe according to the opinion of the European Food Safety Authority. Our supplements also do not contain other dyes, which is particularly important as some dyes can negatively impact activity and concentration, especially in children.
Additionally, we do not use ingredients such as starch or its modifications that could adversely affect the glycemic index (GI).
Dosing Information
Dosing Information
Each bottle contains 30 capsules. Recommended daily dosage is one per day.
Regular price
$89.00 USD
Regular price
$89.00 USD
Sale price
$89.00 USD
Unit price
per
Regulating NAD
1-MNA plays a crucial role in regulating NAD metabolism in the body, blocking the enzyme Nicotinamide N-methyltransferase (NNMT), which is a key regulator of the delicate redox balance, thereby restoring cellular health and optimizing NAD levels.
Award-Winning
Endotelio's 1-MNA is a high-quality dietary supplement, synthesized through a unique technology developed in collaboration with European universities, manufactured in a GMP-certified facility in Eastern Europe, and has been recognized with awards for its groundbreaking contribution to cellular health.
Wide Reaching Benefits
1-MNA has been recognized for its anti-inflammatory and anti-thrombotic properties, along with its unique ability to improve cell energy metabolism.
Understanding 1-MNA Value
How Much Food to Equal One Serving of Endotelio 1-MNA (58 mg)
| Food Item | 1-MNA Content (mg/100 g) | Food Needed to Equal 58 mg (g) |
|---|---|---|
| Wakame seaweed | 3.2 | 1,812 g (1.81 kg) |
| Green tea leaves | 3.0 | 1,933 g (1.93 kg) |
| Poultry stomachs | 2.4 | 2,417 g (2.42 kg) |
| Celery | 1.6 | 3,625 g (3.63 kg) |
| Chinese black mushroom | 1.3 | 4,462 g (4.46 kg) |
| Sea urchin | 1.1 | 5,273 g (5.27 kg) |
| Greater sand eel | 1.1 | 5,273 g (5.27 kg) |
| Natto (fermented soybeans) | 1.0 | 5,800 g (5.80 kg) |
Source: Research data on 1-MNA content in natural food sources
Safety & Tolerability
1-MNA, has vitamin origins and is also found in natural sources. Research has consistently shown that 1-MNA is both safe and well-tolerated in humans. The European Food Safety Authority (EFSA) has conducted a thorough assessment of 1-MNA's safety, confirming its safe usage (1).
(1) EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), Turck D, et al. "Scientific Opinion: Safety of 1-methylnicotinamide chloride (1-MNA) as a novel food pursuant to Regulation (EC) No 258/97." EFSA Journal 2017; 15(10): 5001. Electronic publication available here.
Overall rating: 4.8 / 5 from 15 reviews.
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Review highlights
Reviews
Great product!! IHO is incredibly
"Great product!! IHO is incredibly easy and lively to work with!!"
While I cannot be sure
"While I cannot be sure since I take a lot of supplements, my doctor has me try this with high cholesterol when I did not want to go on medication. In three months my scores came down below the need for meds and I believe this was a factor."
Energy
"Such a cool product! 1MNA has boosted my energy levels and fat loss progress. It helps me stay focused throughout the day without any crash or jittery feelings. I’ve been feeling more motivated and energetic, and it seems to be helping with my overall metabolism as well!"
Loving 1-MNA
"I've been taking 1-MNA for about 10 months now, and feel that it has a great effect on my energy levels. I love it so much I told my parents about it and now they are taking it too. They are seeing a huge effect on their energy levels and it helps them keep working out and enjoying exercise."
Great for Vascular Health
"This supplement has helped improve my circulation and overall heart health. I feel more energized and have noticed a reduction in occasional fatigue. The formula seems to be gentle yet effective, and I appreciate the focus on supporting vascular health. It’s easy to incorporate into my daily routine, and I recommend it to everyone I talk to!"
mental clarity
"I LOVE 1-mna, it helps with mental clarity/energy, and is better than supplementing NAD because 1-mna actually blocks NNMT. I am giving it to all my family for Christmas. It also helps protect my cardiovascular system and brain health."
It improves my endurance a
"It improves my endurance a lot when I take before exercise!!"
I’m taking it but/and haven’t
"I’m taking it but/and haven’t noticed anything"
Incredible product. Keeping me going
"Incredible product. Keeping me going during a tough phase of covid/long covid"
Q&A
Proudly from Colorado
Optimizing Human Potential (OHP Health) originated in the picturesque city of Boulder, Colorado, nestled at the base of the majestic Flatiron mountains. We offer an extensive range of supplements from industry-leading partners, including Prodrome, Arterosil, and Xymogen, among others. Should you have any inquiries, simply utilize the chat feature located at the bottom right of your screen; we're here to assist you from 9 am to 5 pm.